Exam Questions / Microbiology

Questions in gene therapy

Written by MicroDok
  • Describe the term gene therapy.
  • X-ray the differences between in vivo and ex vivo gene therapy techniques.
  • Differentiate between somatic gene therapy and germ line gene therapy.
  • X-ray the applications of gene therapy for treating genetic disorders.
  • Succinctly explain the steps used in gene therapy techniques.
  • What is a codon?
  • Differentiate between start codon and stop codon.
  • Explain the terms transduction and transfection.
  • Differentiate viral vectors from non-viral vectors.
  • A newborn was having problem fighting some infectious diseases; and was later diagnosed with adenosine deaminase (ADA) deficiency. Explain what this diagnosis implies.
  • Mention five uses or applications of gene therapy.
  • What are the ethical issues associated with the application of gene therapy.
  • What is a gene?
  • How does dominant gene differ from recessive gene?
  • What are autosomes?
  • How do autosomes differ from chromosomes?
  • Diagrammatically illustrate the central dogma of molecular biology.
  • Define the term “vector” as it relates to gene therapy techniques.
  • What is genetic code?
  • Draw the structures of adenine, guanine, cytosine, uracil and thymine.
  • Mention the 20 essential amino acids.
  • What is hereditary?
  • How does a genetic disorder differ from an infectious disease?
  • Define restriction enzymes and briefly explain its significance in gene therapy.
  • Succinctly describe the biological significance of adenosine deaminase (ADA) in iving organisms.
  • What are transgenes?
  • Define transfection and transduction.
  • What are harmless viruses?
  • Succinctly describe how gene therapy works
  • For gene therapy to be successful, the right type of vectors must be used. Enumerate the properties of vectors used for gene therapy.
  • Outline the different areas in which gene therapy can be potentially used.

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