Pharmaceutical Microbiology

Multiple Antibiotic Resistance Index (MARI)

Written by MicroDok

Multiple antibiotic resistance index (MARI) is used to determine the multiple antibiotic resistance nature of particular pathogenic bacteria to an array of antibiotics or antimicrobial agents to which the test organism have been previously tested for. MARI helps researchers to know whether or not a particular pathogenic bacterium is multidrug resistant or not. It is calculated using a simple mathematical formular. When calculating MARI, it should only be determined for those bacterial isolates or pathogenic bacteria that showed multiple antibiotic resistances to the different classes of antibiotics used in the general antimicrobial susceptibility testing (AST). The multiple antibiotic resistance index (MARI) of selected multidrug resistant isolates can be calculated using the following formular:

MARI = A/B

A = number of antibiotics to which the resistant bacteria was resistant to.

B = total number of antibiotics to which the resistant bacteria has been evaluated for.

 

References

Ejikeugwu Chika, Duru Carissa, Oguejiofor Benigna, Eze Peter, Okereke Blessing, Eze Nkemdilim, Abani Happiness, Edeh Chijioke (2018). Bacteriological investigation of antibiogram, multiple antibiotic resistance index and detection of metallo-β-lactamase (MBL) in Klebsiella species and Pseudomonas aeruginosa of abattoir origin. Clinical Biotechnology and Microbiology, 2(3):355-360.

Akinjogunla O.J and Enabulele I.O (2010). Virulence factors, plasmid profiling and curing analysis of multidrug resistant Staphylococcus aureus and coagulase negative Staphylococcus spp. isolated from patients with Acute Otitis Media. Journal of American Science, 6(11):1022-1033.

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