Exam Questions / Microbiology

Bacteriology questions

Written by MicroDok
  • Define bacteriology.
  • Explain the different morphological forms or shapes of bacteria.
  • What is inoculum size?
  • What is pathogenicity and virulence?
  • Succinctly explain bacterial toxins and their role in pathogenicity.
  • Differentiate between endotoxins and exotoxins.
  • Briefly describe bacterial extracellular enzymes and their role in pathogenicity.
  • Describe in detail pathogenicity islands.
  • In full details describe the pathogenicity of Bacillus anthracis.
  • Explain the clinical significance of cAMP in the pathogenicity of Vibrio cholerae.
  • Describe in full details the pathogenicity of two Gram-positive cocci and two Gram-negative rods of your choice.
  • Describe the morphology of the causative agent of diphtheria.
  • Why is Haemophilus influenzae often called blood sucking bacterium?
  • What is satellitism?
  • Describe the role of mycolic acid in the pathogenesis and laboratory diagnosis of Mycobacterium tuberculosis.
  • Succinctly explain the Mantoux test.
  • What is botulism?
  • Mention the causative agent of pseudomembranous colitis in man.
  • What is cystitis, bacteremia and septicaemia?
  • Briefly describe urinary tract infections (UTIs) based on their causative agent, pathogenesis, laboratory detection, treatment and prevention and control.
  • In full details describe the five pathogenic strains of Escherichia coli.
  • Briefly describe the morphological appearance of coli, Klebsiella pneumoniae and Pseudomonas aeruginosa on culture/growth media.
  • Explain the pathogenesis of bacterial vaginosis in women.
  • Mention the bacterium that is known as swarming organism.
  • Describe the pathogenicity of any obligate intracellular bacterium of your choice.
  • How does urease production encourage the pathogenesis of Helicobacter pylori?   
  • Succinctly explain the quellung reaction test.
  • Why is Listeria monocytogenes often called a psychrotolerant organism?
  • Explain the phrase listeriosis.
  • What is the causative agent of Lyme disease?
  • Why does Mycoplasma have a stronger cytoplasmic membrane than other bacteria?
  • Describe L-form bacteria.
  • What are biofilms?
  • Describe the significance of quorum sensing in the pathogenesis of pathogenic bacteria.
  • What is quorum sensing?
  • Explain the position of quorum sensing in microbial interactions.
  • What are auto inducers?
  • Explain in detail the different stages involved in the development of biofilm.
  • Briefly name and describe the various shapes of bacteria.
  • What is toxigenicity?
  • Describe in details the features of a pathogenic microorganism.
  • Write a short note on bacterial exotoxins.
  • What are endotoxins?
  • Define enterotoxins.
  • Enumerate the features of bacterial endotoxins and enterotoxins.
  • Briefly describe the various bacterial enzymes involved in bacterial pathogenicity/virulence.
  • Write a short note on the causative agent, pathogenicity, laboratory diagnosis and treatment of listeriosis.
  • Enumerate the net effect of cholera infection in humans.
  • What is the causative agent of traveler’s diarrhea?
  • Explain in details, the medical and industrial significance of actinomycetes.

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