Antimicrobial agents questions

  • Define an antibiotic.
  • Describe in detail antimicrobial agents with examples.
  • What is selective toxicity?
  • Why are there fewer antifungal agents than there are antibacterial agents?
  • Enumerate the characteristics of antimicrobial agents.
  • Differentiate between narrow-spectrum and broad-spectrum drugs with examples.
  • Describe in detail the different target sites of antibacterial agents.
  • What is the therapeutic index of a drug?
  • Mention 3 antibiotics that inhibit cell wall synthesis in bacteria and describe their general mechanism of action.
  • Describe the mechanisms of action of chloramphenicol and tetracyclines.
  • Discuss in details the mechanism of action of a named fluoroquinolone.
  • Enumerate 2 antibiotics that inhibit DNA synthesis and succinctly describe their mechanism of action.
  • Name and describe the mechanism of action of any antimetabolite.
  • Explain in details the mechanism of action of a named aminoglycoside.
  • Succinctly explain the mechanism of action of a named macrolide.
  • Explain the mechanism of action of flucytosine.
  • What are polyenes?
  • List and describe the mechanism of action of any two polyenes.
  • Mention the natural source of griseofulvin?
  • X-ray the antimicrobial potential of interferons against viral agents.
  • Why are there fewer antifungal, antiviral and antiprotozoal drugs than there are antibacterial drugs?

 

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